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Aerials (Rifts Book 1)

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DBS collected from NSP is a valuable resource for studying exposure of newborns to environmental chemicals and for studying temporal trends with exposure to environmental chemicals in newborns. In this study, a gas chromatography-high resolution mass spectrometry method with ultrasonic extraction was successfully applied for the analysis of PCBs and OCPs in DBS samples. This study presents the first evidence of temporal trends of these compounds in DBS specimens collected from newborns during the past two decades. A significant reduction in blood concentrations of PCBs and p,p′-DDE was found between 1997 and 2011. The method developed in this study is applied for a population-based birth cohort with a focus on environmental chemical exposure, couple fertility and children’s health ( Louis et al. 2014). Louis GMB, Sundaram R, Schisterman EF, Sweeney AM, Lynch CD, Gore-Langton RE, Maisog J, Kim S, Chen Z, Barr DB. Persistent environmental pollutants and couple fecundity: the LIFE study. Environmental Health Perspectives. 2013; 121(2):231–236. [ PMC free article] [ PubMed] [ Google Scholar] Louis GMB, Germaine M, Hediger ML, Bell EM, Kus CA, Sundaram R, McLain AC, Yeung E, Hills EA, Thoma ME. Methodology for establishing a population-based birth cohort focusing on couple fertility and children’s development, the Upstate KIDS Study. Paediatric and Perinatal Epidemiology. 2014; 28(3):191–202. [ PMC free article] [ PubMed] [ Google Scholar] Adetona O, Horton K, Sjodin A, Jones R, Hall DB, Aguillar-Villalobos M, Cassidy BE, Vena JE, Needham LL, Naeher LP. Concentrations of select persistent organic pollutants across pregnancy trimesters in maternal and in cord serum in Trujillo, Peru. Chemosphere. 2013; 91(10):1426–1433. [ PMC free article] [ PubMed] [ Google Scholar] Spliethoff HM, Tao L, Shaver SM, Aldous KM, Pass KA, Kannan K, Eadon GA. Use of newborn screening program blood spots for exposure assessment: declining levels of perfluorinated compounds in New York State infants. Environmental Science & Technology. 2008; 42(14):5361–5367. [ PubMed] [ Google Scholar]

But Live Active Leisure board member councillor Brawn – and fellow residents who provided distressing deputations to the committee – believe the failure to close the floodgates in time was more than a contributory factor. But obviously that significantly increased throughout the day to the point around midday/1pm where we had to stop operations. We brought in additional staff to try and support that dynamic risk assessment and make sure we were doing everything we could to prevent water – but it wasn’t possible.Sjödin A, Jones RS, Focant J-F, Lapeza C, Wang RY, McGahee EE. Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States. Environmental Health Perspectives. 2004; 112(6):654–658. [ PMC free article] [ PubMed] [ Google Scholar] By 4pm my staff and I abandoned the venue. Obviously the team did everything they could, they tried to salvage what they could on those intervening hours and make safe electrics as best we could as well.” Burse V, DeGuzman M, Korver M, Najam A, Williams C, Hannon W, Therrell B. Preliminary investigation of the use of dried-blood spots for the assessment of in utero exposure to environmental pollutants. Biochemical and Molecular Medicine. 1997; 61(2):236–239. [ PubMed] [ Google Scholar]

Ha M-H, Lee D-H, Jacobs DR., Jr Association between serum concentrations of persistent organic pollutants and self-reported cardiovascular disease prevalence: results from the National Health and Nutrition Examination Survey, 1999–2002. Environmental Health Perspectives. 2007; 115(8):1204–1209. [ PMC free article] [ PubMed] [ Google Scholar] Rhainds M, Levallois P, Dewailly É, Ayotte P. Lead, mercury, and organochlorine compound levels in cord blood in Quebec, Canada. Archives of Environmental Health: An International Journal. 1999; 54(1):40–47. [ PubMed] [ Google Scholar]Breivik K, Vestreng V, Rozovskaya O, Pacyna J. Atmospheric emissions of some POPs in Europe: a discussion of existing inventories and data needs. Environmental Science and Policy. 2006; 9(7–8):663–674. [ Google Scholar] But just over a year later on Sunday, October 8, the gym and all ground floor areas – including the arena – suffered “considerable damage”. Suyagh MF, Iheagwaram G, Kole PL, Millership J, Collier P, Halliday H, McElnay JC. Development and validation of a dried blood spot-HPLC assay for the determination of metronidazole in neonatal whole blood samples. Analytical and Bioanalytical Chemistry. 2010; 397(2):687–693. [ PubMed] [ Google Scholar] An electromechanical device that works with the help of an electromagnet is called an electric bell. In a classic bell, on applying an electric current, the to and fro movement of a small hammer on a gong would produce the sound of a bell. Thus, an electric bell is an electric device generally used for signalling the presence of a guest or visitor. Numerous studies have shown that POPs elicit adverse health effects in humans, including disruption of endocrine systems as well as reproductive and immunological effects ( Ha et al. 2007; Morales et al. 2013; Tsuji et al. 2013). For example, serum concentrations of PCBs, p,p′-DDE, and HCB were associated with reduced thyroid hormone levels in adult men ( Meeker et al. 2007). High plasma HCB and PCB concentrations were significantly associated with the risk of developing type 2 diabetes ( Wu et al. 2013). An increased risk for obesity was associated with prenatal exposure to PCBs and DDE in children ( Valvi et al. 2012). In comparison with adults, fetuses, newborns, and infants are more sensitive to the effects of environmental chemicals ( Lignell et al. 2013). POPs have been shown to cross the maternal/trans-placental barrier ( Covaci et al. 2002; Jaraczewska et al. 2006). Owing to the administrative and/or legal restrictions in obtaining blood samples for research purposes, little is known regarding the levels of POPs in newborns.

Councillor Brawn explained: “As you would expect LAL [Live Active Leisure] carries the usual fully comprehensive insurance that any other commercial organisation would have. However, following severe flooding of both Bell’s and the Perth Leisure Pool in August 2020, there is an exclusion on surface water flooding.

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In July 2022, Live Active Leisure opened its state-of-the-art 100-plus station gym Bell’s Sports Centre to the public. A report by Perth and Kinross Council’s (PKC) chief executive Thomas Glen admitted floodgates at the North Inch were not closed in time during the extreme weather event on the weekend of October 7 and 8. Otero-Santos SM, Delinsky AD, Valentin-Blasini L, Schiffer J, Blount BC. Analysis of perchlorate in dried blood spots using ion chromatography and tandem mass spectrometry. Analytical Chemistry. 2009; 81(5):1931–1936. [ PubMed] [ Google Scholar] Live Active Leisure chief executive Paul Cromwell said: “Obviously we have experienced floods at Bell’s. That’s widely known. Our last most significant one was 2020 which as everyone will remember was described as a one in 100-year flood – but here we are again.” Persistent organic pollutants (POPs) such as poly chlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) are bio-accumulative, toxic and susceptible to long-range atmospheric transport ( Breivik et al. 2006). Since the 1970s, the use of PCBs and several OCPs was severely restricted or banned in the United States ( Muir and Howard 2006). As a consequence, the levels of these chemicals have decreased in environmental and biological matrixes ( Sun et al. 2006; Venier and Hites 2010). However, detectable levels of PCBs and OCPs have been found in the United States’ general population ( Sjödin et al. 2014). Human exposure and adverse health effects of POPs continue to be of concern despite regulatory efforts to ban the production and use of these chemicals more than 3 decades ago in the United States ( Louis et al. 2013; Taylor et al. 2013; Wu et al. 2013).

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