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Motusol Max 2.32% w/w Gel 30g – Targeted Pain Relief of Joints & Muscles in Acute strains & sprains

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Biotransformation of diclofenac involves partly glucuronidation of the intact molecule, but mainly single and multiple hydroxylation resulting in several phenolic metabolites, most of which are converted to glucuronide conjugates. No accumulation of diclofenac and its metabolites is to be expected in patients suffering from renal impairment. When Motusol Max is applied to a large area of skin and over a prolonged period, the possibility of systemic side-effects (e. uk/Health-%26-Wellbeing/Pain-Relief/Pain-Relief-Gel-%26-Muscle-Rubs/Motusol-Pain-Relief-Gel-Max-2-32%25-50g/p/824700" on this server. Interaction with other medicinal products and other forms of interaction Since the systemic absorption of diclofenac is very low with topical application, interactions are very unlikely in use as intended.

Preventive measures should be taken so that children do not contact the skin areas to which the gel has been applied. Based on conventional studies on safety pharmacology, genotoxicty and carcinogenic potential, the pre-clinical data do not reveal any specific hazards for humans apart from those already described in other sections of the SPC. In animal studies, the chronic toxicity of diclofenac following systemic application mainly manifested as gastrointestinal lesions and ulcers.

Pyrocalm Control Omeprazole 20mg is a One-a-day tablet that provides effective relief from heartburn and indigestion. Due to its properties (such as short plasma half-life, low pKa value, small distribution volume and high protein binding), diclofenac has an affinity to inflamed tissue. Under this circumstance, Motusol should not be applied on the breasts of breast-feeding mothers, nor elsewhere on large areas of skin or for a prolonged period of time (see section 4. When the gel is applied on large areas of skin and over a prolonged period, the possibility of systemic undesirable-effects (e. The quantity of diclofenac absorbed through the skin is proportional to the duration of skin contact and the size of the treated area , and depends on both the total dose applied and the degree of skin hydration.

Voltarol 12 Hour Joint Pain Relief Gel is suitable for people who experience joint pain and inflammation that lasts throughout the day. TENA Discreet Extra are soft, comfortable towels which offer fast, efficient absorbency and give you the ultimate feeling of protection. possible prolongation of bleeding time, an anti-aggregating effect which may occur even at very low doses. If you experience any of the following signs of allergy, stop using Motusol Max and tell a doctor or pharmacist immediately. After applying the gel on the skin you can use a permeable (non-occlusive) bandage but allow the gel to dry on the skin for a few minutes.Do not apply Motusol Max on the breasts if you are a nursing mother nor elsewhere on large areas of skin or for a prolonged period of time. g. renal, hepatic or gastrointestinal side effects, systemic hypersensitivity reactions) - as they occur possibly after systemic administration of diclofenac-containing medicines cannot be completely excluded. Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you. Natures Aid Pro-Daily is a daily supplement containing 5 strains of good bacteria to supplement your microbiome.

Undesirable effects similar to those observed following an overdose of systemic diclofenac can occur if topical diclofenac is inadvertently ingested (1 tube of 100 g contains the equivalent of 1,160 diclofenac diethylamine corresponding to 1,000 mg diclofenac sodium).Depending on the size of the affected site to be treated, cherry to walnut size quantity is required, corresponding to 1 - 4 g of gel (23. There are insufficient data on efficacy and safety in children and adolescents under 14 years of age (see section 4. Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers.

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